Scientifica SliceScope Pro 1000

Overview Technical Data

Integrated electrophysiology system for patch clamp recordings

Integrated electrophysiology system for patch clamp recordings

Scientifica SliceScope Pro 1000

The most popular tissue slice patch clamp electrophysiology system

The SliceScope Pro 1000 is an integrated electrophysiology system for patch clamp recording. The versatility of the system means that you can perform slice electrophysiology, fluorescent imaging, and in vivo experiments.

This package consists of the SliceScope microscope, motorised XY-translation stage, two PatchStar manipulators, adjustable Post & Platform mounting systems, and a recording chamber.

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Product benefits

Record even the smallest electrophysiological signals

The ultra-low noise electronics ensure a high signal-to-noise ratio, meaning you can record tiny signals and acquire the highest data quality every time.

Acquire data from long-term experiments

The incredible stability of the integrated PatchStar Micromanipulators and the sample stage means that you can make long-term recordings from delicate cells and dendrites, enabling full signal acquisition, saving time, and ensuring high-quality data.

Enjoy total control of your rig

The fully integrated PatchStar manipulator, microscope, and sample stage, allow you to smoothly position your electrodes, focus your microscope and align your sample using simple and intuitive remote controls. Since it is so easy to use, even inexperienced users can reliably and confidently acquire data.

Achieve the perfect rig setup for your desired experiment

The SliceScope Pro system’s extreme versatility enables you to position all the components to suit your needs. You have complete freedom to align your manipulators to the perfect angle for patching, position your sample for best access, and set up your rig to meet your experimental needs.

Compact design

The slimline SliceScope and ergonomically designed manipulators and stage create a compact system, providing you with the space you need to add any further equipment to support your unique experimental requirements. Your lab space is also maximised, since the system is mountable on most small lab tables.

Ultimate freedom of manipulator and sample positioning

The ultra-stable manipulator and sample mounting platforms are so versatile that you can mount them anywhere on your rig. The platforms being so compact makes the SliceScopePro 1000 the most popular choice when complete freedom of configuration is required. The swing-in / swing-out function enables you to change sample and pipettes in any way that suits you.

Record from multiple sites of interest

You can confidently search your sample and exchange pipettes during recordings, due to the stability of the sample and manipulators, and smooth movement of the microscope.

A rig for life - Grow your rig with your experiments

The innovative, modular design of the SliceScope Pro enables you to develop and adapt your rig to suit your experimental requirements as they change. If you wish to use IR DIC, fluorescence illumination, optogenetics stimulation or multiphoton imaging, the SliceScope Pro is designed to be able to grow with your research. This saves you precious money and time.

Total customisation and control through software settings

The LinLab 2 software allows you to customise numerous configurations; control speed of movement, select wheel direction, and set memory positions. The easy to use “Follow” function allows you to move the pipettes and sample simultaneously, making cell hunting and patching even easier. To support your complete freedom, you can also choose to control the SliceScope Pro system with your own programming.

Choose your preferred controller to acquire data

Control your rig with a Control Cube or PatchPad - whichever suits you. Both options enable you to control all aspects of your rig, including speed control, memory positions, and home-in and home-out for rapid pipette exchange.

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Scientifica PatchPad Evo

Advanced Control Options

Choose from PatchPad Evo, Control Cube, or LinLab software to control your Scientifica system. PatchPad Evo enhances control with an integrated display that provides real-time coordinate and device information directly on the controller, allowing you to monitor electrode position, track multiple devices, and quickly navigate to stored locations without relying on a separate workstation.

LinLab acts as the central hub for your setup, enabling customisation of movement parameters such as speed, step size, and memory positions, while also providing control of compatible heating and perfusion modules. Features such as Follow enable coordinated movement between devices, supporting efficient and repeatable electrophysiology workflows.

Testimonials

"I always trust Scientifica electrophysiology rigs. The quality is exceptional. The ease of use is additionally important, especially when my laboratory members are training others to perform electrophysiology experiments for the first time. In addition the Scientifica sales and technical support teams are very responsive and helpful through the process of purchasing the rig as well as getting it set up and even checking in to see how things are working. Could not recommend them any higher."

Brady Atwood
University of Minnesota

"As usual, Scientifica did a great job...Scientifica provide the most robust, reliable, and versatile electrophysiology rigs I have seen so far."

Lukas Groschner
Medical University of Graz

"The SliceScope has all the best optical qualities of a top-flight microscope, pared down to-the absolute essentials needed for patch-clamp electrophysiology, and then rebuilt with many highly useful features."

Professor Dimitri Kullmann
Institute of Neurology, UCL

"The Scientifica equipment helps me to achieve goals because it is a formula toolbox. You can go for patch clamp recording, double patch clamp recording, electrical stimulation, optogenetic stimulation, apply pharmacology, all at the same time. So the possibilities are huge."

Dimitri Dumontier
CSHL

"Scientifica's SliceScope Pro 1000 is the Porsche of electrophysiology systems."

Dr. Aikeremu Ahemaiti In Dr. Malin Lagerstorm's Lab
University of Uppsala, Sweden

How customers are using the SliceScope Pro Systems

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Accessories

Scientifica SciCam+ Camera

The Scientifica SciCam+ is a high-performance sCMOS camera designed for patch clamp electrophysiology and fluorescence imaging

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Motorised Objective Changer (MOC)

The Motorised Objective Changer (MOC) can change smoothly between two objectives and display within LinLab which objective is in position. The user has full control over the speed of objective exchange. The intelligent motion allows your objectives to be placed safely into your chamber.

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Scientifica Filter Cube Module+ (FCM+)

The Scientifica Filter Cube Module+ provides high-quality illumination with soft-switch filters and DIC contrast, ideal for delicate experiments like patch clamp recordings.

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Scientifica services for this product

Free Lab Consultations

Your Scientifica specialist can help optimise your lab through a free lab consultation, providing advice on the equipment best suited to your planned experiments and lab space.

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Lab Move Service

Smooth, stress-free lab moves with our expert team. We handle consultation, packing, and re-installing of your electrophysiology system(s). Contact us today!

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Installation & Technical Support

Expert global installation and optimisation of electrophysiology systems. Our team ensures your lab is ready to go. Contact us today!

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Demonstrations

Scientifica offer product demonstrations, allowing you to ask questions, learn about the product and its applications, and see it for yourself.

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Customisations

Customisable microscopes and systems for unique electrophysiology experiments. Our expert team ensures your setup is tailored to your experiments. Contact us to learn more!

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Warranty & Exchange Programme

Scientifica offers a two-year warranty on our products and a one-year warranty on third-party goods. Our Exchange Programme minimises lab disruption and keeps costs down.

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Speak to one of our experts for details on pricing, features, installation and support.

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