Scientifica SliceScope Pro 6000 Electrophysiology Rig
Scientifica SliceScope Pro 6000
Patch clamp electrophysiology system
Patch clamp electrophysiology system
Patch clamp electrophysiology system

Scientifica SliceScope Pro 6000

The most versatile patch clamp electrophysiology system

The SliceScope Pro 6000 is an integrated electrophysiology system for patch clamp recording. The versatility of the system means that you can perform in vitro and in vivo electrophysiology, and even adapt the system for advanced imaging, such as multiphoton imaging and confocal microscopy.

This package consists of the SliceScope microscope, a motorised movable base plate, two PatchStar manipulators, and a recording chamber.

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Product benefits

Record even the smallest electrophysiological signals

The ultra-low noise electronics ensure a high signal-to-noise ratio, meaning you can record tiny signals and acquire the highest data quality every time.

Acquire data from long-term experiments

The incredible stability of the integrated PatchStar Micromanipulators and the sample stage means that you can make long-term recordings from delicate cells and dendrites, enabling full signal acquisition, saving time, and ensuring high-quality data.

Enjoy total control of your rig

The fully integrated PatchStar manipulator, microscope and sample stage, allow you to smoothly position your electrodes and focus and move your microscope to view your sample - using simple and intuitive remote controls. Since it is so easy to use, even inexperienced users can reliably and confidently acquire data.

Achieve the perfect rig setup for your desired experiment

The SliceScope Pro system’s extreme versatility enables you to position all the components to suit your needs. You have complete freedom to align your manipulators to the perfect angle for patching, position your sample for best access, and set up your rig to meet your experimental needs.

A rig for life - Grow your rig with your experiments

The innovative, modular design of the SliceScope Pro enables you to develop and adapt your rig to suit your experimental requirements as they change. If you wish to use IR DIC, fluorescence illumination, optogenetics stimulation or multiphoton imaging, the SliceScope Pro is designed to be able to grow with your research. This saves you precious money and time.

Record from multiple sites of interest

You can confidently search your sample and exchange pipettes during recordings, due to the stable smooth design of the Motorised Moveable Base Plate (MMBP).

Eliminate risk of vibrations

Remote, hands-free control ensures reliable, smooth and confident control of your microscope and manipulators. This removes the risk of introducing vibrations through handling your experiment, as seen in manual systems.

Maximise your patching time with fast, reliable pipette exchange

The PatchStar manipulator incorporates a unique, super-reliable, pipette exchange system which enables you to rapidly change pipettes between experiments. Utilising a simple twist and slide mechanism, you can change your pipette and be ready to patch in seconds. The smart home-in and home-out offset function accounts for varying length electrodes.

Compact design

The slimline SliceScope and ergonomically designed manipulators and stage create a compact system, providing you with the space you need to add any further equipment to support your unique experimental requirements. Your lab space is also maximised, since the system is mountable on most small lab tables.

Ultimate freedom of manipulator positioning

The ultra-stable mounting platform’s holes and sliding carriages means you can position manipulators and other equipment on the same platform providing complete experimental flexibility.

Suitable for in vivo and in vitro

Benefit from unrestricted experimental flexibility and cost advantage by smoothly switching between in vitro and in vivo electrophysiology studies and custom configurations.

Adaptable for your imaging needs

The fixed microscope and moving stage design means that you can easily adapt the system for Multiphoton imaging or develop the rig in whatever way suits you.

Choose your preferred controller to acquire data

Control your rig with a Control Cube or PatchPad - whichever suits you. Both options enable you to control all aspects of your rig, including speed control, memory positions, and home-in and home-out for rapid pipette exchange.

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LinLab is a versatile control software designed to give you advanced control over your motorised Scientifica device.

Advanced Control Options

Control the focus, condenser, translation stage and micromanipulators using our remote control options. Alternatively use our LinLab software, developed specifically to control all of our motorised components and heating and perfusion elements.

Position co-ordinates can be viewed, stored, exported and recalled in LinLab, or users can couple the system with our PatchPad Display Controller, so X, Y and Z co-ordinates can be viewed in real time right by the sample. An ideal set up for customers doing auditory research or anyone who wishes to avoid using a workstation near to their sample.


"For brain slice electrophysiology, the SliceScope Pro 6000 is perfect! It is beautifully designed - there is plenty of space for placing several stimulating and recording electrodes. Many groups of students have learned to patch (and published data!) with this system in only a few weeks! Scientifica clearly has electrophysiology in mind when designing products."

Dr Rebecca Piskorowski
Institute of Psychiatry and Neuroscience of Paris

"The Scientifica stage and manipulators work smoothly out of the box. The microscope system is excellent for visualizing cells for whole-cell patch clamp and can be easily customized to work with a full range of photostimulation approaches we’ve wanted to build in our lab."

Dr Mac Hooks
University of Pittsburgh

"SliceScope Pro 6000 is a very easy to use system with straightforward software, enabling the generation of vital electrophysiological data. The training received from Scientifica was super helpful and any questions we had were answered very promptly."

Dr Qili Liu

"The SliceScope Pro 6000 has a lot of flexibility; the system is compact with a wide workspace thus compatible for multiple cell patching. This means there is an ultra-high degree of freedom to make setting up the manipulators easier. Moreover, the motorised base plate and multiple manipulators are very stable and smooth. These are the reasons why I am happy I chose the SliceScope Pro 6000 to perform multiple cell patching."

Dr Keisuke Kaneko
Children's Hospital of Philadelphia


The Scientifica SciCam Pro Camera

Scientifica SciCam Pro Camera

Use the Scientifica SciCam Pro to visualise beautifully contrasted cells for easier patch clamping and fluorescent Imaging.

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Scientifica Filter Cube Module

Scientifica Filter Cube Module is a compact, flexible and efficient epifluorescence illuminator, optimised for use with LED light engines.

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Motorised Objective Changer (MOC)

The Motorised Objective Changer (MOC) can change smoothly between two objectives and display within LinLab​ which objective is in position. The user has full control over the speed of objective exchange. The intelligent motion allows your objectives to be placed safely into your chamber.

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Download the SliceScope Pro brochure for more information.

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Interview with Dmitri Yousef Yengej (University of Amsterdam)

What's it like using the SliceScope Pro 6000 system?

Watch this video to find out what Dmitri Yousef Yengej (University of Amsterdam) thought about the Scientifica SliceScope Pro 6000 system, including our PatchStar micromanipulators.

Scientifica services for this product

Free Lab Consultations

Your Scientifica specialist can help optimise your lab through a free lab consultation, providing advice on the equipment best suited to your planned experiments and lab space.

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Lab Move Service

Our lab move service includes the pack down and reinstallation of your electrophysiology or multiphoton imaging system.

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Installation & Technical Support

Our installation team can install your system and provide your lab with bespoke training, ensuring your equipment is up and running as soon as possible.

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Scientifica offer product demonstrations, allowing you to ask questions, learn about the multiphoton system and its applications, and see it for yourself.

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Our range of modular parts enable us to tailor our systems to suit your unique research. These can be customised at the point of purchase or later in the lab.

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Warranty & Exchange Programme

Scientifica offer a two-year warranty with all Scientifica manufactured goods and a one-year warranty for third party supplied goods. Giving you peace of mind when purchasing your Scientifica equipment.

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Speak to one of our experts for details on pricing, features, installation and support.

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