Scientifica SliceScope Pro 6000 Electrophysiology Rig

The HyperScope multiphoton imaging system now has advanced imaging capabilities; the introduction of an extended wavelength lens set means you can image deeper and through thin scattering layers in in vivo samples. Learn more here.

Scientifica SliceScope Pro 6000

A full electrophysiology system with a static microscope enabling in vitro and in vivo studies, including advanced imaging such as two-photon imaging and confocal microscopy. The system consists of a SliceScope, motorised movable base plate and two PatchStar micromanipulators.

Benefits

Slimline upright microscope

Easily place equipment around your sample and configure the microscope for specific experimental needs.

Ultra-stable motorised base plate

An electrically quiet, stable and versatile platform with 50 mm of movement in x and y-axes.

Super-smooth micromanipulators

The PatchStar micromanipulators have 20 nm resolution for absolute positioning control.

Modular and Versatile

The perfect foundation for many different configurations or custom designs including in vivo and in vitro electrophysiology and imaging.

Extended Warranty

For a limited time, the warranty of SliceScope Pro rigs has been extended to three years.

Upgradeable

The fixed microscope makes this system ideal for multiphoton or confocal imaging, maintaining optimum laser alignment. If you don’t require these options yet then upgrade as your experiments develop.

Control options

Control the focus, condenser, motorised top plate and micromanipulators from any of our remote control options. Alternatively use Scientifica’s LinLab software, developed specifically to control all of our motorised components.

Downloads

Download the SliceScope Pro brochure for more information.

Testimonials

Watch the video below to find out what Dmitri Yousef Yengej (University of Amsterdam) thought about the Scientifica SliceScope Pro 6000 system, including our PatchStar micromanipulators.


"The Scientifica stage and manipulators work smoothly out of the box. The microscope system is excellent for visualizing cells for whole-cell patch clamp and can be easily customized to work with a full range of photostimulation approaches we’ve wanted to build in our lab."

- Dr. Mac Hooks, University of Pittsburgh

Testimonials

"The Scientifica stage and manipulators work smoothly out of the box. The microscope system is excellent for visualizing cells for whole-cell patch clamp and can be easily customized to work with a full range of photostimulation approaches we’ve wanted to build in our lab."
Dr. Mac Hooks, University of Pittsburgh
“SliceScope Pro 6000 is a very easy to use system with straightforward software, enabling the generation of vital electrophysiology data. The training received from Scientifica was super helpful and any questions we had were answered very promptly.”
Dr. Qili Liu, UCSF

Briand, L., Deutschmann, A., Ellis, A., & Fosnocht, A. (2016). Disrupting GluA2 phosphorylation potentiates reinstatement of cocaine seeking. Neuropharmacology, 111, 231-241. http://dx.doi.org/10.1016/j.ne...

Cao, L-H., Yang, D., Wu, W., Zeng, X., Jing, B-Y., Li, M-T., Qin, S., Tang, C., Tu, Y., & Luo, D-G. (2017). Odor-evoked inhibition of olfactory sensory neurons drives olfactory perception in Drosophila, Nature Communications, 8. https://www.nature.com/article...

Clarke, S., Longtin, A., & Maler, L. (2015). Contrast coding in the electrosensory system: parallels with visual computation. Nature Reviews Neuroscience, 16(12), 733-744. http://dx.doi.org/10.1038/nrn4...

Ferreira, A., Yousuf, H., Dalton, S., & Sheets, P. (2015). Highly differentiated cellular and circuit properties of infralimbic pyramidal neurons projecting to the periaqueductal gray and amygdala. Frontiers In Cellular Neuroscience, 9. http://dx.doi.org/10.3389/fnce...

Giber, K., Diana, M., M Plattner, V., Dugué, G., Bokor, H., & Rousseau, C. et al. (2015). A subcortical inhibitory signal for behavioral arrest in the thalamus. Nature Neuroscience, 18(4), 562-568. http://dx.doi.org/10.1038/nn.3...

Li, J M., & Sheets, P L. (2018). The central amygdala to periaqueductal gray pathway comprises intrinsically distinct neurons differentially affected in a model of inflammatory pain. The Journal of Physiology, 596(24), 6289 - 6305. https://physoc.onlinelibrary.w...

Nath, A., & Schwartz, G. (2016). Cardinal Orientation Selectivity Is Represented by Two Distinct Ganglion Cell Types in Mouse Retina. Journal Of Neuroscience, 36(11), 3208-3221. http://dx.doi.org/10.1523/jneu...

Pappas, A L., Bey, A L., Wang, X., Rossi, M., Kim, Y H, Yan, H., Porkka, F., Duffney, L J., Phillips, S M., Cao, X., Ding, J D., Rodriguiz, R M., Yin, H H., Weinberg, R J., Ji, R R., Wetsel, W C., & Jiang, Y H. (2017). Deficiency of Shank2 causes mania-like behavior that responds to mood stabilizers. JCI Insight. https://insight.jci.org/articl...

Tigaret, C., Olivo, V., Sadowski, J., Ashby, M., & Mellor, J. (2016). Coordinated activation of distinct Ca2+ sources and metabotropic glutamate receptors encodes Hebbian synaptic plasticity. Nature Communications, 7, 10289. http://dx.doi.org/10.1038/ncom...

Vardi, R., Goldental, A., Sardi, S., Sheinin, A., & Kanter, I. (2016). Simultaneous multi-patch-clamp and extracellular-array recordings: Single neuron reflects network activity. Scientific Reports, 6(1). http://dx.doi.org/10.1038/srep...

Williems, J G P., Wadman, W J., & Cappaert, N L M. (2018). Parvalbumin interneuron mediated feedforward inhibition controls signal output in the deep layers of the perirhinal‐entorhinal cortex. Hippocampus, 28(4), 281-296. https://onlinelibrary.wiley.co...

Zeldenrust, F., Knecht, S., Wadman, W., Denève, S.,Gutkin, B. (2017) Estimating the Information Extracted by a Single Spiking Neuron from a Continuous Input Time Series. Frontiers in Computational Neuroscience, 11(49). https://doi.org/10.3389/fncom....

Accessories

Filter Cube Module

A compact, flexible and efficient epifluorescence illuminator, optimised for use with LED light engines. Specifically designed for Scientifica microscopes, the FCM ensures optimal illumination of samples in all possible configurations.

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