Scientifica SliceScope Pro 1000 Electrophysiology Rig

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Scientifica SliceScope Pro 1000

A full electrophysiology system for dual or single patch clamp recording. This package consists of the SliceScope microscope, motorised XY translation stage, two PatchStar manipulators and adjustable Post & Platform mounting systems for the manipulators and sample. Typically used for slice electrophysiology and fluorescent imaging, it is also available in in vivo configurations.


Slimline upright microscope

Easily place other equipment around your sample and configure the microscope for specific experimental needs.

Super-smooth micromanipulators

The PatchStar micromanipulators have 20 nm resolution for absolute positioning control and less than 1 µm drift in two hours for long term experiments.

Fully adjustable post and platforms

Made from high-quality steel and aluminium these ultra-stable platforms can easily be moved to any position desired to gain easy access to the sample.

Modular and versatile

Available in multiple configurations for in vivo and in vitro electrophysiology, with options for fluorescent and confocal microscopy.

Multiphoton imaging options

Future-proof your investment by choosing a system that can be upgraded to multiphoton imaging studies if your experimental requirements change.

Control options

Control the focus, condenser, translation stage and micromanipulators from any of our remote control options.

Alternatively use Scientifica’s LinLab software, developed specifically to control all of our motorised components and heating and perfusion elements.


Download the SliceScope Pro brochure for more information.


““[The SliceScope] has all the best optical qualities of a top-flight microscope, pared down to the absolute essentials needed for patch-clamp electrophysiology, and then rebuilt with many highly useful features"
Professor Dmitri Kullmann, Institute of Neurology, UCL
“Scientifica’s Slicescope Pro 1000 is the Porsche of Electrophysiology Systems”
Dr. Aikeremu Ahemaiti in Dr. Malin Lagerstrom’s Lab, University of Uppsala, Sweden.

Bianchi, V., de Ceglia, R., Chaabane, L., Biffi, E., Bergamaschi, A., & Ferrigno, G. et al. (2012). Brain, Behavior, And Immunity, 45. Retrieved from

Hatch, R., Leinenga, G., & Götz, J. (2016). Scanning Ultrasound (SUS) Causes No Changes to Neuronal Excitability and Prevents Age-Related Reductions in Hippocampal CA1 Dendritic Structure in Wild-Type Mice. PLOS ONE, 11(10), e0164278.

Kolb, I., Stoy, W., Rousseau, E., Moody, O., Jenkins, A., & Forest, C. (2016). Cleaning patch-clamp pipettes for immediate reuse. Scientific Reports, 6(1).

Mapelli, L., Gagliano, G., Soda, T., Laforenza, U., Moccia, F., & D'Angelo, E. (2016). Granular Layer Neurons Control Cerebellar Neurovascular Coupling Through an NMDA Receptor/NO-Dependent System. The Journal Of Neuroscience, 37(5), 1340-1351.

Masuho, I., Ostrovskaya, O., Kramer, G., Jones, C., Xie, K., & Martemyanov, K. (2015). Distinct profiles of functional discrimination among G proteins determine the actions of G protein-coupled receptors. Science Signaling, 8(405), ra123-ra123.

Sutton, L., Ostrovskaya, O., Dao, M., Xie, K., Orlandi, C., & Smith, R. et al. (2016). Regulator of G-Protein Signaling 7 Regulates Reward Behavior by Controlling Opioid Signaling in the Striatum. Biological Psychiatry, 80(3), 235-245.

Zecharia, A., Yu, X., Gotz, T., Ye, Z., Carr, D., & Wulff, P. et al. (2012). GABAergic Inhibition of Histaminergic Neurons Regulates Active Waking But Not the Sleep-Wake Switch or Propofol-Induced Loss of Consciousness. Journal Of Neuroscience32(38), 13062-13075.

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