Introduction to In Vivo Patch Clamp Electrophysiology Webinar | On-Demand

Posted 15th April 2026

Introduction to In Vivo Patch Clamp Electrophysiology Webinar | On-Demand

Delivered in partnership with the British Neuroscience Association (BNA), this webinar offered a comprehensive introduction to in vivo patch clamp electrophysiology, a powerful approach for measuring neuronal activity with high temporal and spatial resolution.

The session delivered by Dr Rebecca Jordan (PI, University of Edinburgh) and Dr Soraya Meftah (Snr Research Fellow, University of Edinburgh) explored both the core principles and real-world application of the technique sharing practical insight into how in vivo patch clamp is implemented in cutting-edge studies.

The on-demand version of this webinar is available on request. Please click on the button below to request a link (please note you will need a google account).

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Why watch?

  • Gain a clear understanding of how in vivo patch clamp recordings are performed in both awake and anaesthetised preparations
  • Learn how electrophysiological techniques are used to investigate neural circuits, behaviour, and disease
  • Explore practical considerations, including experimental setup, data acquisition, and troubleshooting
  • Discover how these methods are applied in current research, from studying sensory processing and prediction to understanding neurodegenerative disorders

By combining technical guidance with real-world case studies, this on-demand webinar is designed to support researchers at all levels looking to incorporate electrophysiology into their work.

Scientifica IVM Triple Manipulator

Scientifica IVM Triple

Motorised XYZ in vivo electrophysiology micromanipulator with extended travel range for brain mapping and flexible positioning workflows.

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Scientifica IVM Mini Triple micromanipulator

Scientifica IVM Mini Triple

Compact XYZ in vivo electrophysiology micromanipulator for multi-probe recordings and flexible positioning in dense experimental setups.

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in vivo microscope for electrophysiology and behavioural studies

Scientifica VivoScope

An upright in vivo microscope for electrophysiology and behavioural studies, compatible with treadmills, stereotaxic frames, and VR setups.

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Dr Rebecca Jordan

Principal Investigator, University of Edinburgh

Dr Rebecca Jordan is Principal Investigator and Simons ESAT Fellow at the University of Edinburgh, where she leads the Prediction and Plasticity Lab within the Centre for Discovery Brain Sciences. Her research focuses on how the brain learns to predict sensory input and integrate sensory and motor information to support perception and behaviour. She uses a combination of cutting-edge systems neuroscience techniques, including in vivo electrophysiology, two-photon imaging, optogenetics, and virtual reality paradigms, to investigate cortical circuit function and learning mechanisms.

Dr Rebecca Jordan, Principal Investigator, University of Edinburgh

Dr Soraya Meftah

Senior Research Fellow, University of Edinburgh

Dr Soraya Meftah is a Postdoctoral Research Fellow at the UK Dementia Research Institute and Centre for Discovery Brain Sciences at the University of Edinburgh. Her research focuses on the neurophysiology of dementia, investigating synaptic, neuronal, and network dysfunction in neurodegenerative diseases such as Alzheimer’s. She has extensive experience in both in vivo and in vitro patch clamp electrophysiology, alongside advanced techniques including imaging and molecular approaches. Her work combines high-resolution electrophysiology with translational disease models, including studies using live human brain tissue, to better understand early circuit dysfunction in neurodegeneration.

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Dr Soraya Meftah, Senior Research Fellow, University of Edinburgh

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