Scientifica VivoScope
The VivoScope is a slimline upright microscope. When combined with a multiphoton scan head, it forms the foundation of the finest in vivo imaging system for two-photon behavioural studies.
The VivoScope is ideal for larger in vivo samples, linear or spherical treadmills, large stereotaxic frames or other virtual reality set-ups. The extended position of the scan head gives more room between the light path on your sample and the microscope frame.
The VivoScope microscope frame is available with resonant or galvo scan heads and a variety of detectors including the MDU, MDU XL, ChromoFlex and FLIM Upgrade kit. Take a look at our buyer’s guide to see our full multiphoton range and all scan head, frame and detector options available.
Multiphoton Imaging Systems Buyer's Guide
The VivoScope in action at the Allen Institute
The Allen Institute for Brain Science is using three VivoScopes to collect data for the Allen Brain Observatory, an ongoing project to visualise the brain in action. Watch the video below for more information:
Design & Specifications
| Scanning mirror (y-galvo) | 3 x 5 mm 8315KL scanning mirror (MicroMax 671HP driver) |
|---|---|
| Scanning mirror (x-galvo) | 2 kHz in bidirectional scan mode (4 fps @ 512x512 px), 1 kHz in unidirectional scanning mode (2 fps @ 512x512 px) |
| Scanning mirror (x-resonant) | 3 x 5 mm 8 kHz CRS series scanner from Cambridge Technologies (15 fps @ 1024 x 1024 px, 30 fps @ 512 x 512 px, 60 fps @ 512 x 256 px) |
| Beam input height | 280.6 mm |
| Input beam diameter | <3 mm |
| Beam diameter at back aperture | <20.1 mm |
| Beam expansion | 6.7x |
| Relay lens expansion | 1x |
| Lens coating | 700-1200 nm (Rav <0.5%) |
| Maximum scan angles (galvo) | +/- 10 optical degrees |
| Maximum scan angles (scan head) | +/- 7.6 optical degrees |
| Galvo voltage/optical degree | 0.25 V |
| Turning mirror size | 45 x 64 x 6 mm |
| Turning mirror coating | Protected Silver (98% reflectivity) |
| Typical field of view | ~600 µm2 (16x), ~500 µm2 (20x) |
| Scan control | SciScan, ScanImage 5 |
Schematics
VivoScope moving microscope with a Tiltable Objective Mount (TOM) and 100um Piezo
Research Papers
Accessories
Movable Periscope Bracket (MP-4010-30)
This bracket attaches the periscope directly to the XY stage allowing the customer to move the microscope in X and Y whilst maintaining perfect laser alignment.
Filter Cube Module
A compact, flexible and efficient epifluorescence illuminator, optimised for use with LED light engines. Specifically designed for Scientifica microscopes, the FCM ensures optimal illumination of samples in all possible configurations.
