Watch on-demand: Advancements in multielectrode recording techniques in neurophysiology

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Watch on-demand: Advancements in multielectrode recording techniques in neurophysiology

On Thursday 12th August, Scientifica hosted the 'Advancements in multielectrode recording techniques in neurophysiology: From wire probes to Neuropixels' webinar in partnership with the British Neuroscience Association (BNA).

Dr Kris Schoepfer, US Product Specialist at Scientifica, began the webinar by presenting an introduction to in vivo multichannel recordings, discussing the benefits of using multichannel recordings to understand neurophysiology. Following this, they shared the considerations for planning these experiments, as well as the equipment required. Lastly, Kris introduced the array of multielectrode technologies currently available, and the pros and cons of each.

Following this, keynote speaker, Dr Sylvia Schröder, Sir Henry Dale Fellow at the University of Sussex, presented her exciting data from the optic tract and superior colliculus, sharing how this was acquired using Neuropixels probes. Sylvia highlighted the advantages of these probes, which include channel depth and the new biologicals insights they enable. Lastly, Sylvia discussed how the Neuropixels recordings and optogenetics can be combined.

Relevant papers

On Neuropixels 1.0:

  • Jun, Steinmetz, Siegle, Denman, Bauza, Barbaritis, Lee et al. (2017, Nature)

On Neuropixels 2.0:

  • Steinmetz, Aydin, Lebedeva, Okun, Pachitariu et al. (2021, Science)

On recordings from optic tract:

  • Schröder et al. (2020, Neuron)

Chronic recordings:

  • Juavinett, Bekheet, Churchland (2019, eLife)
  • Luo, Bondy et al. (2020, eLife)
  • Van Daal et al. (2021, Nat Protoc)

IVM Triple Motorised Micromanipulator

A versatile three axis motorised manipulator that enables precise, controlled positioning of pipettes and probes, including Neuropixels probes and microelectrode arrays (MEAs). The long travel and ultra-smooth motion make this micromanipulator the perfect solution for in vivo experiments.


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