The HyperScope multiphoton imaging system now has advanced imaging capabilities; the introduction of an extended wavelength lens set means you can image deeper and through thin scattering layers in in vivo samples. Learn more here.
Scientifica IVM Single
A versatile single axis motorised manipulator that enables precise, controlled positioning of pipettes and probes, including neuropixels probes and microelectrode arrays (MEAs). Ideal for a range of electrophysiology experiments, including field recordings and patch clamp, as well as microinjection experiments.
Compatible with stereotaxic frames, the long travel and ultra-smooth motion make this micromanipulator the perfect solution for in vivo experiments.
Benefits
Maximises tissue health
Smooth probe insertion into the brain. Using the unique 'creeper' function to precisely control the movement of the manipulator, your probe can 'creep' to the desired position at a speed of your choice. This minimises tissue damage, reduces gliosis and increases the signal quality and data you receive from neurons.
Accurate positioning
Hit your precise target every time by programming the IVM to move to the exact brain region you are interested in, at a speed of your choice. The IVM has 20 nm resolution for absolute positioning. View the exact position of your probe using dedicated software and/or the Patch Pad display.
Perform long-term experiments
The high stability of the design ensures you can maintain position in the brain for reliable, long-term experiments.
High signal-to-noise ratio
The smooth approach, minimises tissue damage, maximises the signal-to-noise ratio and improves histology outcomes.
Audibly quiet
The low-noise electronics minimise disturbance to the sample and allows smaller signals to be detected.
Focus on your sample
The hands-free movement allows you to concentrate on the welfare of your sample during probe positioning. The risk of human error is reduced, which reduces wasted animals and time, increasing your experimental efficiency.
High stability
The continuous, smooth motion of the manipulator causes minimal vibrations compared to the stop-start motion of a manual manipulator. This improves accuracy and reduces damage, so you can draw reliable conclusions from your results.
Reach deep within your sample
The long 70mm range of travel means you can probe deep into your sample.
Compact
The IVM-1000 takes up less room, ideal if you are limited on space.
Control options
Operate via our ergonomically designed remote control options or through our specially designed LinLab software.
What is the unique 'creeper' function?
The creeper function in LinLab allows the movement of the manipulator to be programmed over a set distance at a pre-defined speed. This allows for smooth motion to the correct area of interest.
Alternatively, the step function can be used for faster, yet measured step movement to insert the electrode into the cell.
Downloads
Download the IVM Single brochure for more information.
Design & Specifications
| Number of axes | 1 |
|---|---|
| Travel distance | 70 mm |
| Electronic resolution | 20 nm |
| Minimum step size | 0.1 µm |
| Minimum speed | 1 µm per second |
| Maximum speed | 4 mm per second |
| Memory positions | 50 on control device (unlimited via LinLab) |
| Software | LinLab for Windows |
Schematics
Research Papers
Accessories
Dovetail Probe Holder (PH-1000)
Dovetail probe holder to fit bars/probes
Extended Right Angled Kopf Mount (IVM-650-00)
Allows the user to mount the IVM in one of four mounting positions on the Kopf or Stoelting manipulator.
LBM-7 Adjustable Mount (IVM-510-00)
This allows the approach axis of the LBM-7 to be removed, enabling the IVM be mounted in its place. It can then be rotated and locked in position at the correct angle.
LBM-7 Fixed Mount (IVM-505-00)
Allows the user to mount the IVM on the LBM-7 either to the approach axis stage or to the sliding carriage attached to the approach axis. If mounted on the approach axis stage it can only do so in the same axis as the stage. If mounted on the sliding bracket it can be mounted at 90º or in the same axis as the approach axis.
Extended Probe Holder
To hold capillary glass of 1-2 mm in diameter.
Right Angled Kopf Mount (IVM-520-00)
Allows the user to mount the IVM in a single mounting position on the Kopf or Stoelting manipulator.