The HyperScope | Ideal for in vivo multiphoton imaging

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Scientifica has optimised and extended the long wavelength performance of the HyperScope


The HyperScope multiphoton imaging system now has advanced imaging capabilities; the introduction of an extended wavelength lens set means imaging can now be performed using the full 900 – 1700nm wavelength range – ideally suited for in vivo imaging of green and red fluorescence proteins.

With the full in vivo imaging range covered, researchers can image deeper and through thin scattering layers in in vivo samples. Cleaner, more useable data can be acquired using the longer wavelengths. Imaging through superficial layers is possible with a reduced need for invasive surgeries.


The mouse neocortex labelled with CellTracker green. Acquired at 1100um depth using three-photon excitation on Scientifica’s Multiphoton microscope, using an Amplitude Mango SP for excitation. Data kindly provided by Dr Adam Packer, University of Oxford.

These extended capabilities make the HyperScope ideal for GFP and RFP two- and three-photon imaging. Existing HyperScopes can be upgraded to the new lens set to extend the experiments you can do with this system. Contact your local representative to learn more about upgrading, or find out more about the HyperScope here.

Scientfica HyperScope

Image deeper and see more than ever before using the HyperScope multiphoton imaging system. The introduction of an extended three-photon lens set ensures the full in vivo imaging range is covered, allowing you to image deeper and through scattering layers.

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