Scientifica SciCam Pro Camera
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    The HyperScope multiphoton imaging system now has advanced imaging capabilities; the introduction of an extended wavelength lens set means you can image deeper and through thin scattering layers in in vivo samples. Learn more here.

    Scientifica SciCam Pro Camera

    The SciCam Pro is a high resolution CCD camera specifically designed for use with electrophysiology setups. It is ideal for fluorescence imaging, live cell imaging, calcium imaging and electrophysiology.

    Built in collaboration with scientific camera experts QImaging, the fanless cooling system and built-in grounding point create zero vibration and electrical noise for careful electrode positioning and fine electrophysiological recordings.

    Benefits

    Fanless cooling

    Cooling fins create a heat sink to enable fanless cooling for completely vibration-free imaging.

    Fast frame rates

    50 MHz pixel digitisation delivers fast frame rates for smooth visualisation of electrode positioning in electrophysiology.

    Integrated grounding point

    Electrically isolate the whole camera with ease.

    High sensitivity

    75% peak QE enables the detection of weak signals not possible on industrial cameras, making the SciCam Pro ideal for low-light fluorescence imaging and calcium imaging.

    Pristine images

    Intelligent Quantification algorithms enable Defective Pixel Correction (DPC) to provide flawless, high-quality images.

    Regulated sensor cooling

    Regulated sensor cooling provides high-quality images for long experiments.

    Download the SciCam Pro Datasheet

    Camera Comparison Guide

    Applications

    • Electrophysiology
    • Fluorescence microscopy
    • Calcium imaging
    • Live cell imaging
    • Infrared DIC

    Software

    The SciCam Pro is packaged with QImaging's Ocular software. Designed from the ground up, it is the ideal software choice for image capture in microscopy. The software can be easily installed and enables intuitive image capture.

    Learn more about the Ocular software

    Merged Widefield IR and Fluorescence Images

    Fluorescence images of in vivo 6DPF zebra fish larvae expressing GCamp6, imaged using the SciCam Pro camera

    Widefield Fixed Cell Fluorescence Images

    Widefield fluorescence images captured using the SciCam Pro camera. From left to right: Bovine Pulmonary Artery Endothelial Cells labelled with AlexaFluor 488 phalloidin for F-actin; Mouse kidney section stained with Alexa Fluor® 488 wheat germ agglutinin; Muntjac skin fibroblast labelled with green fluorescent Alexa Fluor® 488 phalloidin for F-actin.

    Design & Specifications

    CCD Sensor
    CCD Sensor
    Sensor Type
    Sensor Type
    Sony ICX-825 Scientific Interline CCD (Monochrome)
    CCD Array
    CCD Array
    1360 x 1024
    Pixel Size
    Pixel Size
    6.45μm x 6.45μm
    Sensor Dimensions
    Sensor Dimensions
    8.8mm x 6.6mm (11mm diagonal)
    Peak Quantum Efficiency
    Peak Quantum Efficiency
    75% at 600nm
    Full Well Capacity
    Full Well Capacity
    >11,000e- single pixel
    Camera
    Camera
    Digital Output
    Digital Output
    14-bit with 50MHz readout
    Digitization Rate
    Digitization Rate
    USB3: 50MHz high frame rate
    Read Noise (typical)
    Read Noise (typical)
    <5.5e- RMS with 50MHz readout
    Frame Rate
    Frame Rate
    22 fps (full resolution), 31 fps (binned 2x2)
    Exposure Time Range
    Exposure Time Range
    25µs - 5secs
    Supported Binning Modes
    Supported Binning Modes
    1x1, 2x2, 4x4, 6x6, 8x8, 12x12, 16x16
    Dark Current Rate (typical)
    Dark Current Rate (typical)
    0.036 e/p/s at +15ºC regulated
    Sensor Cooling
    Sensor Cooling
    0ºC stabilised at 22ºC ambient, Thermoelectric cooling with convection
    Intelligent Quantification Features
    Intelligent Quantification Features
    DPC - Defective Pixel Correction
    Interfacing
    Interfacing
    Computer Platforms/Operating Systems
    Computer Platforms/Operating Systems
    Windows 7 (64 bit), Windows 8 (64 bit), Windows 10 (64 bit). Refer to the QImaging website for the latest list of minimum computer recommendations
    Digital Interface
    Digital Interface
    USB3.0 (USB2 compatible at reduced max fps)
    Triggering I/O Signals
    Triggering I/O Signals
    Trigger In, Expose Out, End-of-Frame, Shutter Out
    Supported Triggering Modes
    Supported Triggering Modes
    Trigger First, Strobe, Bulb
    Shutter Modes
    Shutter Modes
    Open Never, Open Pre-exposure, Open Pre-sequence, Open Pre-trigger, Open no change
    Mechanical
    Mechanical
    Optical Interface
    Optical Interface
    1”, C-mount optical format
    Mounting Hole Thread Size
    Mounting Hole Thread Size
    1/4” - 20 thread, 4 sides
    Camera Dimensions
    Camera Dimensions
    98.4mm x 76mm x 76mm (length x width x height)
    Weight
    Weight
    1.55lb, 0.72kg
    Power Requirement
    Power Requirement
    7.5V DC, 2.5A

    Research Papers

    Annecchino, L., Morris, A., Copeland, C., Agabi, O., Chadderton, P. and Schultz, S. (2018). Robotic Automation of In Vivo Two-Photon Targeted Whole-Cell Patch-Clamp Electrophysiology. Neuron, 95(5), p1048–1055 http://dx.doi.org/10.1016/j.ne...

    Booker, S., Sumera, a., Kind, P. and Wyllie, D. (2021). Contribution of N-methyl D-aspartate receptors to synaptic function in rat hippocampal interneurons. eNeuro, https://doi.org/10.1523/ENEURO...

    Gelegen, C., Miracca, G., Ran, MZ., Harding, EC., Ye, Z., Yu, X., Tossell, K., Housten, CM., Yustos, R., Hawkins, ED., Vyssotski, AL., Dong, HL., Wisden, W., and Franks, NP. (2018). Excitatory Pathways from the Lateral Habenula Enable Propofol-Induced Sedation. Cell Press, 28(4), p580-587. https://www.sciencedirect.com/...

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