Position: PhD student 100%
Location: The Department for Endocrinology, Diabetology and Clinical Nutrition of the University Hospital Zurich, Switzerland
Start date: 01/02/2024
About the position
Arterial hypertension, affecting 20% of the population and escalating with age, poses a significant cardiovascular risk. Primary aldosteronism (PA), the main cause of secondary hypertension, results from excessive aldosterone production in the adrenal glands. The Department for Endocrinology, Diabetology and Clinical Nutrition of the University Hospital Zurich in collaboration with the Electrophysiology Facility at UZH, is looking to appoint a PhD student in the context of the University Research Priority Program ITINERARE: Innovative Therapies in Rare Diseases - Challenges and Opportunities. The candidate's main duty is to advance a research project investigating potential therapeutic opportunities to treat endocrine tumours caused by mutations in ion channels and transporters. The primary location of research will be in the Irchel Campus of UZH.
- Develop and implement high throughput electrophysiological and imaging methods to interrogate large libraries of compounds.
- Analyze and report data.
- Maintain detailed records of protocols and experiments.
- Collaborates closely with researchers with different expertise for implementation of experimental pipeline and data analysis.
- Independent implementation of biological experiments such as cell culture, cloning, CRISPR-Cas9, Western blot, PCR, qRT-PCR, ELISA, histology, immunostaining and microscopy.
- MSc in Biology, Biochemistry, Pharmacology, Biomedicine or related fields.
- Team player
- Familiar with electrophysiological techniques. High Throughput Automated Patch Clamp would be an asset.
- Experience in cell culture and molecular biology techniques.
- Good communication skills in English and German (plus).
- Analysis of large datasets using R or similar platforms.
What UZH offer
The University of Zurich stands out as an attractive place to work due to its vibrant community, characterized by a strong sense of involvement and commitment from everyone, including researchers, teaching staff, students, and supporting staff. The university offers well-equipped, conveniently located spaces, including physical and virtual environments. Moreover, UZH prides itself on its rich diversity, being the largest university in Switzerland, bringing together individuals from diverse disciplinary, cultural, and linguistic backgrounds, enriching the academic learning experience and enhancing collaborative opportunities.
Start of employment
01.02.2024 or upon agreement. This position last initially four years, starting in the first trimester of 2024 upon agreement. The goal of this position is to obtain a PhD title. The approval within the Life Science Zurich Graduate School is mandatory for this position and must be obtained within the first year of appointment.
How to apply
Please submit in a single PDF
- letter of motivation
- curriculum vitae
- short summary of past research accomplishments
- transcripts of your academic records from your university, and a copy of your degree
- contact details of two referees (e.g. your M.Sc. thesis supervisor)
Before 12th of December 2023 to Prof. Felix Beuschlein
For more details visit the UZH website.