Optimising Cardiovascular Patch Clamp Workflows with the PatchScope Pro System
In many cardiovascular labs, the patch clamp setup is anything but simple — rigs are often put together from many suppliers. While that approach might work, it comes with compromises: unexpected noise, drift, managing multiple purchases, and a battle with compatibility. This impacts your data quality, slows your progress, and can put experiments and publications at risk.
You deserve a system ready to deliver results. Cells and time are limited, so you don’t want to waste it troubleshooting.
This is where Scientifica’s PatchScope Pro is a game-changer.
Built for Patch Clamp Experiments
The PatchScope Pro is a complete, unified system — designed by electrophysiologists who understand the daily realities of patch clamping.
Every component, from micromanipulator to microscope, staging to software, is engineered to work seamlessly together — eliminating the trial-and-error setup and inconsistent performance of mismatched rigs.
The result? The rig works with you. Generating the data that fuels discoveries.
Motorised Precision for Fragile, Contractile Cells
Patching cardiomyocytes requires more than precision — it requires stability. Even minor vibrations or manual adjustments can compromise a seal or damage your cell.
The PatchScope Pro is fully motorised. You can reposition, refocus, and align electrodes remotely — protecting your prep and maintaining control throughout the experiment.
With ultra-stable, programmable control across all functions, the PatchScope Pro enables:
- Acquisition of data from long-term experiments
- Greater seal success
- Motorised transitions between cells, more cells patched
- Faster, more repeatable workflows
PatchScope Pro: A patch clamp rig that works with you
Clean Signals, Trusted Data
Cardiomyocytes are highly sensitive to interference — thermally, mechanically, and electrically. The wrong rig doesn’t just introduce noise; it buries your signal and impacts your results.
The PatchScope Pro is built to preserve data integrity at every level:
- Solid structure prevents pipette drift and maintains seal stability
- Compact, shielded design reduces grounding problems and external noise sources.
- Ultra-low-noise electronics ensure clean, stable recordings — even with small signals or over long protocols.
When you're working with difficult cells and tight timelines, you can't afford signal instability.
The PatchScope Pro works smoothly straight out of the box. The microscope system is excellent for visualising cells for whole-cell patch clamp. It can be easily customised to work with a full range of photostimulation approaches we’ve wanted to build in our lab.
Braulio Munoz, PhD Indiana University School of MedicineMake Every Cell Count
Cardiomyocyte patching is a race against time. Delays in setup, manual realignment, or fiddly adjustments eat into your window for usable data.
The PatchScope Pro is designed to help you patch more:
- Fast pipette exchange with home-in/home-out to keep patching
- Tag cells of interest and return to them at the push of a button
- ‘Follow’ function that tracks your cell and moves the electrode alongside it
- Fully motorised platform that speeds up transitions and reduces manual errors.
Fewer missed patches. More usable data.
The PatchScope Pro is designed to help you patch more
One Supplier. Full Support.
With the PatchScope Pro, everything comes from a single trusted source — no need for you to coordinate with multiple suppliers or chase down answers when something changes.
From your first consultation with our team of electrophysiologists to installation and long-term support, we work with you to ensure the system fits your research now and evolves with it.
It’s not just about convenience — it’s about protecting your time and keeping your focus where it belongs: on the research.
Unlock More and Better Data — With a Rig That Works With You
Let us show you how PatchScope Pro can help you patch cells easier, collect data faster, and simplify your cardiac workflows. Simply submit the form, and let's discuss your research.
Scientifica PatchScope Pro Systems
Scientifica PatchScope Pro 3000
The perfect hands-free patch clamp rig for pharmacological and network studies. Designed by electrophysiologists, for electrophysiologists.
Scientifica PatchScope Pro 2000
A complete patch clamp rig, perfect for pharmacological studies or other cultured cell stimulation. Designed by electrophysiologists, for electrophysiologists.
Scientifica PatchScope Pro 1000
The perfect patch clamp rig for cultured cell electrophysiology. Designed by electrophysiologists, for electrophysiologists.
Scientifica PatchScope
An ultra-stable, motorised inverted microscope that can be integrated with your existing manipulators.
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