Photometrics Prime BSI Scientific CMOS Camera

Delivering the perfect balance between high resolution imaging and sensitivity with an optimized pixel design and near perfect 95% Quantum Efficiency.

This 4 Megapixel camera with 6.5µm pixels captures highly detailed images at high frame rates, making it the most versatile sCMOS for live cell imaging techniques, including Total Internal Reflection Fluorescence (TIRF), Ratiometric Imaging and Lightsheet microscopy.

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Product benefits

High quantum efficiency 95% peak QE

Maximises ability to detect weak signals, enables short exposure times for high frame rates, minimises phototoxicity across a wide range of wavelengths.

Optimized 6.5µm pixel size

Maximise light collection while maintaining proper spatial sampling at 60X.

Extremely low read noise

Maximise your ability to detect faint fluorescence.

Fast frame rates

Capture highly dynamic events with high temporal resolution.

Large field of view

Maximise the number of cells that can be tracked and monitored per frame.

PrimeEnhance™

Real-time quantitative denoising algorithm that improves image clarity by reducing photon-shot (Poisson) noise | Delivers an increase in Peak Signal to Noise Ratio of 3X

PrimeLocate™

Dynamically evaluates and acquires only the relevant data for localisation based super-resolution applications.

Enhanced dynamic range

Measure both bright and dim signal levels within the same image | 35,000:1 Dynamic Range (91 dB).

Multiple expose out triggering

Control up to four light sources for multi-wavelength acquisitions.

SMART Streaming™

Faster acquisition rates with variable exposures, ideal for multi-probed live cell imaging.

Additional information

Prime BSI delivers a 100% pixel fill factor and does not rely on micro-lensing technology to increase detection, resulting in a 30% increase in sensitivity over previous sCMOS cameras.

This perfect balance in performance makes the Prime BSI the most versatile imaging camera for live-cell imaging with: