Simultaneously image and photostimulate hundreds of individual cells in 3D, with precise targeting of cells across large areas of the brain. Introducing the HoloStim-3D.
Molecular Devices MultiClamp 700B Amplifier
A microelectrode amplifier that combines leading edge electronics design and a wealth of features and functions with an intuitive user interface that simplifies the creation of complex protocols.
For single-channel recordings, whole-cell voltage- and current-clamp recordings, intracellular sharp electrode recordings, extracellular field potential recordings in ion channel, neuroscience, nanopore and voltammetry studies
Support of up to four headstages
Makes the MultiClamp 700B System four amplifiers in one
Software control of all amplifier settings
Automated optimization features; reduction of manipulation steps; and convenient; reliable telegraphing
Fast, reproducible application switching
Quick Select Feature recalls up to three saved amplifier configurations
Easy monitoring of membrane and cell health parameters
Integrated seal test in voltage- and current-clamp mode
Dual Command Potential
Add flexibility by processing input signals from two different sources.
Selectable command sensitivity for flexible control of the output waveform.
Pipette offset compensation with auto-mode quickly removes signal offsets.
Automatic pipette capacitance
Automatic pipette capacitance compensation requires only the push of a button to neutralize the contribution of the glass pipette and the pipette holder to the capacitance of the circuitry.
Series resistance compensation: Prediction helps achieve the desired command level faster by transiently supercharging the membrane potential.
Series resistance compensation
Correction improves the bandwidth of the recording by eliminating the error introduced by the voltage drop across the series resistance.
Automatic cell capacitance compensation corrects for the capacitance of the cell membrane in whole-cell recordings with a single mouse click.
Automatic mode switching enables you to control the transition between voltage and current clamp by an external trigger or depending on the recorded signal.
Automatic oscillation detection prevents damage to a cell when electrical feedback occurs.
Leak subtraction for automatic correction of leak currents with a smart, software-based algorithm.
Selectable output gain with 11 settings to scale the output signal to the desired level.
Audio monitor for acoustic tracking of the signal while you are busy looking down a microscope.
Fine tunable 4-pole bessel and butterworth low-pass filters act as anti-aliasing filters and can be used to pre-condition the output signal.
Dimensions (in.)3.5 (H)x 19 (W) x 12 (D)
Dimensions (cm)8.9 H) x 48.3 (W) x 30.5 (D)
Weight10 lbs. (4.54 kg)
Headstage (in.)0.875 (H) x 1.625(W) x 2.3125 (D)
Headstage (cm)2.0 (H) x 4.0 (W) x 8.4 (D)
Channels2 (sharing a common ground)
CommunicationsUSB 1 Type B female ports
Rack useStandard 19" rack-mount (2U) with handles
Benchtop useBayonet feet
Power85-260 VAC, 50-60 Hz, 30 W (max)
SafetyCE marking (Conformité Européenne)
Frontiers in Molecular Neuroscience