Scientifica Multiphoton Detection Unit (MDU)

Acquire high-quality images and maximise your photon collection when performing multiphoton fluorescence imaging

The MDU is an optimised one or two-channel fluorescence detection system specifically designed for multiphoton imaging with a range of objectives.

It offers high sensitivity with a choice of Photon Multiplier Tubes (PMTS) to suit your sample and experimental needs. The MDU has been optimised for integration with Scientifica's microscopes and can be added to your existing setup.

The MDU boasts pre-aligned optics, safety shutters/switches, a changeable filter cube, and a choice of PMTs, providing a complete solution for your imaging detection needs. Each detection unit includes a power supply, and control unit for convenient operation and integration with your Data Acquisition System.

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Product benefits

Clearer and more detailed images

The optical design of the MDU ensures you capture scattered light emitted from the objective, resulting in maximised image quality. You can obtain the highest possible signal intensity and resolution, leading to clearer and more detailed images.

Maximum photon collection at wide scan angles

The MDU has a fixed-position collection lens positioned close to the objective's pupil. The collection lens is optimised to capture photons emitted at various angles during the scanning process. Enabling you to obtain detailed imaging data over a large field of view.

Exceptional image quality

The MDU’s electronics are engineered to maximise the signal-to-noise ratio. This means that you will achieve clearer images and higher-quality data, even with dim samples.

Ease of experimental setup

The MDU offers an easy experimental setup with fast filter exchange when examining different wavelengths. It is also compatible with existing Scientifica microscopes and easy to integrate into custom-built systems. This saves you time and effort when switching between applications or preparations.

Consistent collection efficiency

The MDU employs detectors that move with the focus drive. This unique feature ensures that the collection efficiency remains constant regardless of the position of the focus, improving the accuracy of your imaging experiments.

Tailor to your experiments

The MDU offers a range of detector options to ensure the right fit for your specific application (PMT, GaAsP, Gated GaAsP). You can also fit different objectives onto the MDU. These features give you experimental flexibility depending on your need.

Increased photon capture

The MDU maximises light collection from a wide range of objectives and even through a substage condenser. Photons can be harvested from objectives that have either small or large back apertures.

Improved PMT lifespan

The MDU incorporates a protection circuit that safeguards your PMTs by automatically shutting them down in the presence of high ambient light levels. This feature enhances the lifespan of the PMTs, ensuring their long-term performance.

Remote PMT control

The MDU offers the convenience of remote PMT control through software. With this feature, you can control your PMT gain directly from your computer's imaging software interface via the USB connection.

Perform transmitted or epifluorescent applications

The MDU incorporates a safety shutter that provides protection for the PMTs during transmitted or epifluorescent applications. The safety shutter is positioned over the PMT optical path and acts as a barrier, preventing ambient light from reaching and damaging the PMTs.

Ready to use optics

The MDU features prealigned optics, eliminating the need for adjustments and ensuring maximum photon collection without any additional setup steps.

Above or below sample

Collect reflected fluorescence through the microscope objective, or transmitted fluorescence using a high-NA oil-immersion condenser lens. Alternatively, combine two MDUs simultaneously for optimum signal collection in up to four channels.

Achieve greater control during optogenetics experiments

With gated GaAsP PMTs, you can have greater control when performing optogenetics experiments. This is because they enable the PMT to be desensitised for pulses of up to 10ms, whilst light stimulation is being applied.