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Location: Clermont-Ferrand, France
Start date: Jan, 2019
Closing date: 30 Nov, 2018
A 3-year postdoctoral position funded by the French National Agency for Research (ANR) grant is available starting January 2019 in the group of Pr. Radhouane Dallel, at the Neuro-Dol Laboratory (Clermont-Ferrand, France). Neuro-Dol is affiliated with the French National Institute of Health and Medical Research (INSERM) and the University Clermont-Auvergne (UCA).
The laboratory is located in an exceptional environment in France that is affordable, challenging and highly recognized for its technical and scientific expertise. Located at the CHU Estaing Hospital, it was recently built in 2013 and offers a large (~ 750 m2) and modern working area with high standards. The team studies the cellular and molecular mechanisms of spinal and trigeminal pain in order to implement new treatment strategies. They combine preclinical (behavioral analysis, ex vivo and in vivo electrophysiology, mathematics, immunohistochemistry, confocal and multi-photon laser scanning microscopies, western blotting and quantitative RT-PCR, …) and clinical (epidemiology, quantitative sensory testing (QST), electroencephalography (EEG), transcranial magnetic stimulation (TMS) and mathematic tools,…) approaches to investigate the neurobiological basis of pain and its control.
A highly motivated, independent and well organized individual, is sought to conduct a research project, in collaboration with Dr. Patrick Carroll (Institute for Neurosciences of Montpellier), on the role of mechanosensory primary neurons in the establishment and function of pain circuits within the spinal dorsal horn. The project combines cutting-edge patch-clamp whole cell electrophysiology, living cell imaging and behavioral analysis in genetically modified mice. Applicants must hold a PhD in Neuroscience and have a genuine interest in experimental biology. The successful candidate should be hard-working, self-motivated, and comfortable with surgical procedures in rodents. In addition, experience in patch clamp electrophysiology and/or multi-photon imaging is needed.