Postdoc Position at the Insitute of Psychiatry and Neuroscience of Paris

We have a variety of multiphoton imaging systems, electrophysiology rigs, manipulators and staging available at a reduced price. Find out more here.

Duration of position: 2 years

Start date: As soon as possible

Website: https://ipnp.paris5.inserm.fr/...

The Position

We are looking for a postdoctoral fellow with expertise in electrophysiology, optogenetics, in vivo recordings and/or behavior and who has a special interest in regeneration. The post-doc candidate will integrate our team located in the new Institut of Psychiatry and Neuroscience of Paris (IPNP) inside Sainte-Anne Hospital, a highly stimulating environment.

When myelination is impaired or myelin is destroyed in the CNS, cognitive, motor and sensory functions are compromised. Despite the low regeneration capacity of the CNS, a spontaneous production of newly formed oligodendrocytes and a partial myelin repair can occur in response to a demyelinating injury. We recently showed that a moderate neuronal activity in vivo improves myelin repair by increasing both the density of OLs and myelin production in demyelinated lesions, inducing a remarkable functional recovery (Ortiz et al., 2019). The present project aims to determine the mechanisms allowing neuronal activity to improve myelin repair and, in turn, action potential conduction.

​Recent relevant publications of the team:

  • Orduz D et al., (2019) Nat Commun 10:4249
  • Ortiz FC et al. (2019) JCI Insight 4(9):e123434
  • Balia M et al. (2017) Glia 65(11):1821-1832
  • Wake H et al. (2015) Nat Commun 6:7844
  • Orduz D et al. (2015) eLife 4:e06953

How to Apply

Interested candidates should send their CV, a motivation letter including research interests and names of 2 referees to: [email protected].

Please mention that you saw this job on Scientifica's website when applying.

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