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Role: Postdoctoral position on “Neuronal polarity and synaptic specificity in mouse retina”
Location: Aarhus, Denmark
Employment start date: 1st June, 2019
Research Area and Project Description
A funded two-year postdoctoral position is available as soon as possible in a research group where structure, function and development of neural circuits in visual system are studied. We combine molecular biological, genetic, viral, electrophysiological, imaging, and behavioral approaches to understand how neural circuits are assembled (Yonehara et al., Nature 2011; Neuron 2016) and function (Yonehara et al., Neuron 2013) in retinas as well as higher visual centers by focusing on the role of cell types.
The purpose of the postdoc is to study how neuronal polarity and spatially asymmetric neuronal connectivity of motion-sensitive neurons in the mouse retina are established by molecular and cellular mechanisms during development. We have already identified some master genes, knock out of which lead to impaired spatially asymmetric neuronal connectivity and retinal motion sensitivity, similarly to Frmd7 we identified before (Yonehara et al., Neuron 2016). The postdoc is expected to study the signaling cascades of identified molecules using molecular, biochemical, cell biological, transcriptome, proteome, viral vector, and in vivo genome editing approaches.
Qualifications and Specific Competences
For this postdoc position we are looking for a highly motivated scientist who has a strong background in molecular biology, biochemistry, cell biology, and/or developmental neurobiology. Applicants must have PhD degree in neurobiology or related field. The successful candidate is expected to have strong skills in English.
The appointment is for two years with the possibility of further extension. A competitive salary and access to state-of-the-art research facilities will be provided.