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Position: A PhD position is available to work on the sensorimotor integration in the trigeminal and thalamic sensory relay nuclei during the sleep-wake cycle
Location: Lyon, France
Closing date: Open until filled
A PhD position is available to work at the Lyon Neuroscience Research Center (CRNL, University UCB-Lyon 1) on a project investigating how sensory information is transferred and gated from the periphery to the cortex in wakefulness and sleep, using the anatomically well-defined whisker somatosensory system as a model. This project will combine state-of-art electrophysiological methods with optogenetics in head-fixed mice, and will also involve the use of anatomical and behavioral techniques.
Publications related to the project
N. Urbain, N. Fourcaud-Trocmé, S. Laheux, P.A. Salin and L.J. Gentet. Brain-state-dependent modulation of neuronal firing and membrane potential dynamics in the somatosensory thalamus during natural sleep. Cell Report, 2019, 26: 1443-1447.
N. Urbain, P.A. Salin, P.A. Libourel, J.C. Comte, L.J. Gentet and C.C. Petersen. Whisking-related changes in neuronal firing and membrane potential dynamics in the somatosensory thalamus of awake mice. Cell Report, 2015, 13: 647-656.
T. Furuta, N. Urbain, T. Kaneko and M. Deschênes. Corticofugal control of vibrissa-sensitive neurons in the interpolaris nucleus of the trigeminal complex. Journal of Neuroscience, 2010, 30: 1832-1838.
N. Urbain and M. Deschênes. Motor cortex gates vibrissal responses in a thalamocortical projection pathway. Neuron, 2007, 56: 714-725.
N. Urbain and M. Deschênes. A new pathway of vibrissal information processing modulated by the motor cortex. Journal of Neuroscience, 2007, 27: 12407-12412.
P. Lavallée, N. Urbain, C. Dufresne, H. Bokor, L. Acsádi and M. Deschênes. Feedforward inhibitory control of sensory information in higher order thalamic nuclei, Journal of Neuroscience, 2005, 25: 7489-7498.
The candidate should hold a Masters degree, with a strong background in either neurosciences or physics/engineering. The ideal candidate has previous experience in experimental work or signal analysis. Programming skills are desired but not required. We are searching for an applicant with a high commitment and curiosity about neuroscientific questions.
How to Apply
Interested candidates with recently completed Masters are invited to send their application (including a letter of intent, CV, list of completed university courses and the name of a scientific referee) to Dr Nadia Urbain ([email protected]).