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npi electronic PDES - Pneumatic drug Ejection
PDES - Pneumatic Drug Ejection npi units are designed for pressure ejection of drugs in physiological and pharmacological studies.
PDES systems can be equipped with high pressure outputs (up to Pmax = 4 bar / 87 psi) for drug application with fine-tipped micropipettes or with low-range pressure output for controlled droplet application from large-tipped pipettes. Analog (standard) or digital timers (optional) and a remote control unit facilitate the use of these instruments.
Each system is housed in a 19" cabinet that can be mounted in a rack. It comprises of two channels. Each channel consists of a precision pressure regulator, an analog (or digital) pressure display, digital (or analog) timer, electronically controlled valves, control electronics and a regulated power supply. Ejection of drugs can be activated manually or via a TTL input. The operational status is indicated by a red / green LED. Each channel is equipped with an "EXHAUST" coupling whereby a low "retain" pressure can be applied (analogous to the "retaining" current used in iontophoretic systems).
PDES systems are available with valves located in the controller or very fast application, with a micro valve located in an injection pipette holder (microJECT).
Source gasAir, nitrogen, helium etc., no aggressive, combustible or explosive gases, filtered by a 5 μm filter element
Input pressureMax 5 bar (72psi)
|Pressure control range||
Pressure control range0-4 (0-58psi)
|Residual air pressure||
Residual air pressure10 mbar (0.145 psi) to 100 mbar (1.45 psi)
|Input and output couplings||
Input and output couplingsQuick connect type
TubesInput: 6mm OD
|Output: 4mm OD|
Mode selectionThree position toggle switch (TIMER, CONT., EXT.)
|Minimum valve switch time||
Minimum valve switch timeStandard valve: approx. 10ms dependent on the tubing length with microJECT: < 1ms
Digital timer100 μs - 10 s set by five digit switch (0000.0 - 9999.9 ms)
Analog timer0.001 - 0.1 s, 0.01 - 1 s, 0.1 - 10 s and 1 - 100 s linear control, range set by toggle switch time base selector (0.01 s, 0.1 s, 1 s, 10 s)
|Pulse input (BNC connector)||
Pulse input (BNC connector)For external operation: TTL (LO= 0-2.5 V, HI= 3-5 V) input impedance: 10 k
|Timing output (BNC connector)||
Timing output (BNC connector)TTL (LO= 0-2.5 V, HI= 3-5 V) output impedance: 249 Ω
|Pressure output (BNC connector)||
Pressure output (BNC connector)Pressure monitor:, sensitivity: 1 V/bar or 0.1 V/psi, output impedance: 249 Ω
|Remote control (option)||
Remote control (option)Toggle switch and status LED for each channel, size: 2.5 x 4 x 10cm
Dimensions19" rackmount cabinet, 19" (483 mm), 10" (250 mm), 3.5" (88mm)