The VivoScope goes galvo

The HyperScope multiphoton imaging system now has advanced imaging capabilities; the introduction of an extended wavelength lens set means you can image deeper and through thin scattering layers in in vivo samples. Learn more here.

The VivoScope goes galvo


The Scientifica VivoScope, ideally suited to two-photon in vivo behavioural studies, is now available with a galvanometer scan head for increased experimental flexibility.

Scientifica VivoScope

The finest in vivo imaging system for two-photon behavioural studies. Ideal for larger in vivo samples, linear or spherical treadmills, large stereotaxic frames or other virtual reality set-ups.

The “galvo” scanning path contains a separated pair of 3 mm galvanometer mirrors to direct your laser to any point within the field of view. This arrangement offers a number of advantages including variable scanning speeds and highly flexible scan patterns.

Using Scientifica’s SciScan software you can set your system to acquire unidirectional full field images (2 frames per second (fps) at 512 X 512 pixels (px)) or bidirectional full field images (4 fps at 512 x 512 px). Further scanning configurations include arbitrary line scans, patterned point scanning and region of interest scanning.

Additionally, reducing your scan speed instead of relying on averaging can achieve the same improvement in signal-to-noise ratios with less bleaching and tissue damage.

Like the resonant VivoScope system, this microscope also increases the space between the light path and your sample (in comparison to our Multiphoton Imaging System), this creates enough room for the use of small animals (e.g. mice and rats), linear or spherical treadmills, large stereotaxic frames or other virtual reality set-ups. It does so without compromising the stability or slim profile of the frame.

The system is tailored to the use of large back aperture objectives and enables significantly deeper imaging for in vivo behavioural studies than a standard fluorescence microscope.

The photons emitted from your sample are collected by either our original Multiphoton Detection Unit placed above the objective or using ChromoFlex, with up to four GaAsP PMTs placed remotely from the microscope via a liquid light guide.

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